Frequently Asked Questions

What causes cervical cancer?

Virtually all cervical cancers are caused by an HPV infection. Most HPV infections do not cause cancer and resolve naturally without requiring treatment. But if an HPV infection persists, critical cellular changes such as cervical DNA damage can occur, putting the patient at higher risk of (pre)cancer.

How do I know if I am at risk?

You may be at risk for cervical cancer if:
  • Your PAP test result is abnormal
  • Your HPV test is positive

Why do I need another test?

Your PAP test result may be abnormal for many reasons unrelated to cervical cancer. HPV is very common. In fact, 8 out of 10 women will test positive for HPV by the age of 50, but only a small number are expected to progress to cervical cancer.

How do I know if I have DNA damage?

The Cervical DNA Dtex® test can identify DNA damage of the cervical cells.

What is the Cervical DNA Dtex® test?

The Cervical DNA Dtex® test analyzes genomic instability at a cellular level where cancer occurs. Cervical cell changes such as DNA damage are associated with the development of cervical cancer. (References)

What will the Cervical DNA Dtex® test results tell me?

  • If the Cervical DNA Dtex® test is “Positive” (>2 copies of 3q, 5p and/or CEN 7), DNA damage to the cervical cells has occurred
  • If the Cervical DNA Dtex® test is “Negative” (2 copies of 3q, 5p and CEN 7), no DNA damage was detected in the sample analyzed

Am I a Candidate for the Cervical DNA Dtex® test?

The Cervical DNA Dtex® test  may benefit women who either test positive for HR-HPV or present with a mild cytological abnormality such as ASCUS (Atypical Squamous Cells of Undetermined Significance) or LSIL (Low-grade Squamous Intraepithelial Lesion). The Cervical DNA Dtex® test is performed directly from the PAP Test sample previously collected (ThinPrep® or SurePath™). For additional information, please consult your physician.

Is the Cervical DNA Dtex® test reimbursed by my insurance?

The Cervical DNA Dtex® test may be reimbursed by government and private payers. Please contact your insurance provider for specific details regarding your plan or the performing laboratory to verify any potential patient responsibility.